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MONDAY, Feb. 26, 2024 (HealthDay Information) — Hormone alternative remedy may assist ladies keep away from melancholy as they undergo menopause, a brand new examine finds.
Ladies handled with hormone remedy at a menopause clinic in Ontario, Canada, skilled a discount of their signs of melancholy, researchers report Feb. 21 within the journal Menopause.
This enchancment occurred whether or not or not antidepressants have been additionally prescribed, outcomes confirmed.
“This examine confirmed a helpful impact of hormone remedy on temper signs throughout menopause when used alone and a synergistic impact when utilized in mixture with antidepressants,” mentioned Dr. Stephanie Faubion, medical director for The Menopause Society.
“It additionally highlights the excessive prevalence of temper signs throughout this transition and the necessity to deal with ladies’s signs holistically fairly than having a singular give attention to sizzling flash administration,” Faubion added in a society information launch.
Despair has been proven to be notably more likely to happen across the time of menopause, researchers mentioned.
On this examine of 170 ladies, about 62% of members scored as “depressed,” mentioned researchers led by Dr. Alison Shea, from The Analysis Institute of St. Joseph’s Healthcare in Hamilton.
Hormone remedy has been proven to successfully handle sizzling flashes, however its capacity to handle mood-related signs is much less established, researchers mentioned in background notes.
Hormones affect the mind pathways that regulate temper throughout and after menopause, and are thought to play a job in depressive signs, the researchers mentioned.
The toll of all of the bodily signs that accompany menopause additionally might dampen ladies’s moods, they added.
Ladies who went by way of pure menopause skilled important enchancment of their signs of melancholy, researchers discovered.
Nonetheless, ladies who went by way of menopause as a consequence of most cancers therapy or surgical procedure didn’t have comparable enhancements, outcomes confirmed.
Extra data
Johns Hopkins Drugs has extra on menopausal hormone remedy.
SOURCE: The Menopause Society, information launch, Feb. 21, 2024
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